RxAdvance is now a part of nirvanaHealth. Click here to learn more.

Prescriber Resources

Prior Authorization (PA) Review

Depending on the type of medication and whether any additional information is needed to process the PA request, the review process can take one day, a few days, or longer. Your assigned RxAdvance PA contact will guide you through the process if additional information is required. Please contact the Member Services Center at the number listed on the Contact Us page if you have questions about the PA review process or would like to request a printed copy of a PA policy.

Click here for our Prior Authorization Policies

Submitting a PA (Preferred Methods)

RxAdvance uses CoverMyMeds (CMM) for electronic prior authorizations (ePA). To submit an ePA, visit CoverMyMeds.

You can submit a PA via fax after downloading our Prior Authorization form. The PA forms are available here.

Peer-to-Peer Requests

RxAdvance offers prescribers a Peer-to-Peer review when an adverse determination has been issued. A Peer-to-Peer review will be conducted between two (2) licensed health care providers to discuss the clinical details of an adverse determination of a product or service. The Peer-to-Peer review is considered part of the initial decision process, not part of the appeals process.

A Peer-to-Peer review can be requested, verbally or in writing, within two weeks following the date of the notice of adverse determination. A request for Peer-to-Peer review beyond the two-week timeframe will be processed as an appeal. A Peer-to-Peer review may be requested for adverse determinations of medical necessity, not administrative denials. A Peer-to-Peer review will not be performed or scheduled if a formal appeal has already been filed.

The clinical reviewer will discuss the adverse determination and any clinical information used to render the determination with the prescriber. Submission of any additional clinical information after an adverse determination is made is considered an initiation of an appeal.

For your convenience in scheduling a Peer-to-Peer review, RxAdvance has a Peer-to-Peer request form available here.

Requesting an Appeal

If an unfavorable decision is rendered for a prior authorization, step therapy override, formulary exception, coverage exception, or quantity limit exception, instructions regarding the appeals process will be included in the decision notification. Additional contact information will be provided. Please contact RxAdvance Consumer Services at 877-281-1745 (TTY: 711) if you have questions about an appeal.

For an appeal to be processed as urgent, it must meet the legal definition of urgent. Generally, an urgent situation is one in which the health of the member may be in serious jeopardy or, in your opinion, the member may experience pain that cannot be adequately controlled while waiting for the appeal decision. For urgent requests, RxAdvance has up to seventy-two (72) hours from the time of receipt to respond with a decision. For non-urgent appeals, RxAdvance has up to thirty (30) days from the date of receipt to respond with a decision.

For your convenience, RxAdvance has an appeals form available here.

Please send the appeal to the following address:
Attn: Clinical Appeals
136 Turnpike Road,
Southborough, MA 01772

Fax: 508-452-0076 (for standard appeals requests)
508-452-6421 (for urgent appeals requests)


We will respond to you as soon as we can.

RxAdvance is now nirvanaHealth.

Since 2013, the RxAdvance team has been dedicated to disrupting the healthcare industry, specifically in pharmacy benefit management. After 3 years of development, we went live with our first client in 2016 and delivered groundbreaking pharmacy benefit management services. Now that we have proven success year-after-year, we have decided to expand our impact beyond just the PBM industry—onto the payer industry. These two industries alone control the majority of the healthcare spend in the United States, including the $900+ billion of waste generated annually. With our expansion into a new portion of the industry, we have outgrown the RxAdvance name, since it does not accurately capture the scope of our healthcare reach and mission. We are excited to announce our new name and brand—nirvanaHealth. The RxAdvance name has served us well for many years and will continue to do so under nirvanaHealth.